Metyrosine - CISMeF

Preferred Label : Metyrosine;

NCIt synonyms : Metirosine; methyl-tyrosine; Alpha-methyl-p-tyrosine;

NCIt definition : A methylated tyrosine, a catecholamine synthesis antagonist with antihypertensive property. Metyrosine competitively inhibits tyrosine 3-monooxygenase, an enzyme that activates molecular oxygen to catalyze the hydroxylation of tyrosine to dihydroxyphenylalanine (Dopa), an intermediate to catecholamine (dopamine, norepinephrine, and epinephrine) production. This agent reduces the elevated levels of catecholamines associated with pheochromocytoma, thereby preventing hypertension.;

UNII : DOQ0J0TPF7;

InChIKey : NHTGHBARYWONDQ-JTQLQIEISA-N;

CAS number : 672-87-7;

Drug name : Demser;

Molecule name : MK-781; L-588357-0;

Chemical formula : C10H13NO3;

ChEBI ID : CHEBI:6912;

Details

Origin ID

C998;

UMLS CUI

C0886584;

Automatic exact mappings (from CISMeF team)
- Metirosine [ICHI extension code]
- alpha-Methyltyrosine [MeSH Descriptor]
- methyltyrosines [MeSH concept]
- methyltyrosines [MeSH Descriptor]
Currated CISMeF NLP mapping
- Metirosine [ICD-11 Extension code]
- Metirosine (substance) [SNOMED CT concept]
- metyrosine [Substance BNPC]
- metyrosine [MeSH concept]
- metyrosine [SNOMED Notion]
See also inter- (CISMeF)
- Product containing metirosine (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Metirosine [ICD-11 Extension code]
- Metirosine (substance) [SNOMED CT concept]
- Product containing metirosine (medicinal product) [SNOMED CT concept]
- metirosine [ATC Code]
- metyrosine [Substance BNPC]
- metyrosine [MeSH concept]
- metyrosine [SNOMED Notion]
Validated automatic mappings to BTNT
- metirosine [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients