Preferred Label : Adagloxad Simolenin;
NCIt definition : A carbohydrate-based immunostimulant comprised of the Globo H hexasaccharide 1 (Globo
H) epitope linked to the immunostimulant carrier protein keyhole limpet hemocyanin
(KLH), with potential antineoplastic activity. Upon administration of adagloxad simolenin,
the carbohydrate antigen Globo H may stimulate a cytotoxic T-lymphocyte (CTL) response
against Globo H-expressing tumor cells, thereby decreasing tumor cell proliferation.
Globo H is a tumor associated antigen (TAA) commonly found on a variety of tumor cells
including breast cancer cells. KLH improves antigenic immune recognition and T-cell
responses.;
UNII : UCG949AA7Z;
CAS number : 1458687-85-8;
Molecule name : OBI 822; OBI-822;
NCI Metathesaurus CUI : CL433491;
Origin ID : C99766;
UMLS CUI : C4688640;
Semantic type(s)
- concept_is_in_subset
- has_target
