SENP6/NKAIN2 Fusion Gene

Preferred Label : SENP6/NKAIN2 Fusion Gene;

NCIt synonyms : SUSP1-TCBA1 Fusion Gene; TCBA1/SUSP1 Fusion Gene; SENP6-NKAIN2 Fusion Gene; SUSP1/TCBA1 Fusion Gene; SENP6::NKAIN2 Fusion Gene;

NCIt definition : A fusion gene that results from a chromosomal deletion del(6)(q13q21) which fuses nucleotide 551 of the SENP6 gene to exon 4 of the NKAIN2 gene. The fusion is out of frame with the NKAIN2 gene. This rearrangement was described in a T-cell lymphoma/leukemia cell line called HT-1.;

NCIt note : Nucleotides 489 to 509 of the SENP6 gene were deleted in the chimeric transcript. (Genes Chromosomes Cancer. 2002; 34:175-85.);

Details

Origin ID

C99688;

UMLS CUI

C1857982;

Automatic exact mappings (from CISMeF team)
- Na+/k+ transporting atpase-interacting 2 [OMIM gene]
- Sentrin-specific protease family, member 6 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
related_to_genetic_biomarker
- NKAIN2 Gene [NCIt concept]
- SENP6 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients