ABL1/BCR Fusion Gene

Preferred Label : ABL1/BCR Fusion Gene;

NCIt synonyms : ABL1-BCR Fusion Gene; ABL1::BCR Fusion Gene;

NCIt definition : A fusion gene that results from a chromosomal translocation t(9;22)(q34;q11) that fuses the extreme 5' portion of the ABL1 to part of the 3' portion of the BCR gene. This rearrangement is associated with chronic myelogenous leukemia, acute lymphoblastic leukemia and acute myeloid leukemia.;

NCIt note : The ABL1/BCR gene may or may not be expressed. (Atlas of Genetics and Cytogenetics in Oncology and Haematology);

Details

Origin ID

C99683;

UMLS CUI

C1861019;

Automatic exact mappings (from CISMeF team)
- Abl protooncogene 1, nonreceptor tyrosine kinase [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
related_to_genetic_biomarker
- ABL1 Gene [NCIt concept]
- BCR Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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