" /> ADGRG1 wt Allele - CISMeF





Preferred Label : ADGRG1 wt Allele;

NCIt synonyms : GPR56; TM7XN1; TM7LN4; BFPP; DKFZp781L1398; UNQ540/PRO1083; Adhesion G Protein-Coupled Receptor G1 wt Allele; BPPR; G Protein-Coupled Receptor 56 Gene;

NCIt definition : Human ADGRG1 wild-type allele is located in the vicinity of 16q13 and is approximately 45 kb in length. This allele, which encodes adhesion G-protein coupled receptor G1 protein, plays a role in both cell-cell signaling and brain development. Mutation of the gene is associated with bilateral frontoparietal polymicrogyria.;

NCIt note : Expression of the GPR56 gene downregulates VEGF production in melanoma cells and inhibits melanoma angiogenesis and growth. (Cancer Res. 2011; 71: 5558-5568.); Expression is analyzed as part of the 17-gene leukemia stem cell scoring system (LSC17). (Nature. 2016; doi:10.1038/nature20598.);

GenBank Accession Number : AJ011001;

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29/07/2025


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