SPIB wt Allele

Preferred Label : SPIB wt Allele;

NCIt synonyms : SPI-B; Spi-B Transcription Factor (Spi-1/PU.1 Related) wt Allele;

NCIt definition : Human SPIB wild-type allele is located within 19q13.3-q13.4 and is approximately 10 kb in length. This allele, which encodes transcription factor Spi-B protein, plays a role in the positive regulation of transcription.;

NCIt note : Deletion of the SPIB gene has been linked to pre-B cell acute lymphoblastic leukemia. (Blood. 2011; 118: 2801-2808.);

GenBank Accession Number : NM_003121;

Details

Origin ID

C99652;

UMLS CUI

C3274851;

Automatic exact mappings (from CISMeF team)
- Spi-B transcription factor [ORDO Gene]
- Spib transcription factor [OMIM gene]
OMIM relation
- Spib transcription factor [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 19q13.3-q13.4 [NCIt concept]
gene_plays_role_in_process
- DNA Binding [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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