CDK6/MLL Fusion Gene

Preferred Label : CDK6/MLL Fusion Gene;

NCIt synonyms : MLL/CDK6 Fusion Gene; CDK6-MLL Fusion Gene; CDK6::KMT2A Fusion Gene; CDK6::MLL Fusion Gene;

NCIt definition : A fusion gene that results from a complex chromosomal aberration which fuses exon 2 of the CDK6 gene with exon 10 of the MLL gene. This fusion may be associated with infant acute lymphoblastic leukemia.;

NCIt note : The CDK6/MLL fusion was found in a patient that also had a MLL/AFF1 fusion gene.;

PubMed : 11930009;

Details

Origin ID

C99589;

UMLS CUI

C1863997;

Automatic exact mappings (from CISMeF team)
- Cyclin-dependent kinase 6 [OMIM gene]
- Lysine-specific methyltransferase 2a [OMIM Phenotype]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CDK6/MLL Fusion Protein [NCIt concept]
related_to_genetic_biomarker
- CDK6 Gene [NCIt concept]
- KMT2A Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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