NCIt definition : A fusion gene that results from a chromosomal translocation t(1;14)(q25;q32) which
places the LHX4 gene on the 5' side of the coding sequence for the IGHG1 gene. This
rearrangement is associated with acute lymphoblastic leukemia.;
NCIt note : This translocation allows the expression of the LHX4 gene to be controlled by the
IgG heavy chain promoter, which causes overexpression of the LIM/homeobox protein
Lhx4.;