" /> LHX4/IGHG1 Fusion Gene - CISMeF





Preferred Label : LHX4/IGHG1 Fusion Gene;

NCIt synonyms : LHX4-IGHG1 Fusion Gene; IGHG1/LHX4 Fusion Gene; LHX4::IGHG1 Fusion Gene;

NCIt definition : A fusion gene that results from a chromosomal translocation t(1;14)(q25;q32) which places the LHX4 gene on the 5' side of the coding sequence for the IGHG1 gene. This rearrangement is associated with acute lymphoblastic leukemia.;

NCIt note : This translocation allows the expression of the LHX4 gene to be controlled by the IgG heavy chain promoter, which causes overexpression of the LIM/homeobox protein Lhx4.;

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07/05/2025


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