NCIt synonyms : exp1; DKFZp686B1823; Exportin 1 wt Allele; emb; CRM1; CRM1, Yeast, Homolog Gene; Required For Chromosome Region Maintenance Gene; Exportin-1 (Required For Chromosome Region Maintenance) Gene; Exportin 1 (CRM1 Homolog, Yeast) Gene;
NCIt definition : Human XPO1 wild-type allele is located in the vicinity of 2p15 and is approximately
61 kb in length. This allele, which encodes exportin-1 protein, is involved in the
modulation of nuclear transport.;
NCIt note : Mutation of the XPO1 gene may be associated with chronic lymphocytic leukemia. (Nature.
2011; 475: 101-105.);