DDX10/NUP98 Fusion Gene

Preferred Label : DDX10/NUP98 Fusion Gene;

NCIt synonyms : DDX10-NUP98 Fusion Gene; DDX10::NUP98 Fusion Gene;

NCIt definition : A fusion gene that results from a chromosomal inversion inv(11)(p15q22) which fuses the first half of the NUP98 gene to the 3' portion of the DDX10 gene. This fusion is associated with both with de novo and therapy-related acute myeloid leukemia and myelodysplastic syndrome.;

NCIt note : Putative fusion protein product is not considered clinically relevant.;

Details

Origin ID

C99445;

UMLS CUI

C1832870;

Automatic exact mappings (from CISMeF team)
- Dead-box helicase 10 [OMIM gene]
- Nucleoporin, 98-kd [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_has_abnormality
- inv(11)(p15;q22) [NCIt concept]
related_to_genetic_biomarker
- DDX10 Gene [NCIt concept]
- NUP98 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients