ETV6/ABL2 Fusion Gene

Preferred Label : ETV6/ABL2 Fusion Gene;

NCIt synonyms : TEL/ARG Fusion Gene; ABL2/ETV6 Fusion Gene; ETV6/ARG Fusion Gene; TEL-ARG Fusion Gene; ETV6-ABL2 Fusion Gene; ETV6::ABL2 Fusion Gene;

NCIt definition : A fusion gene that results from a chromosomal translocation t(1;12)(q25;p13) which fuses exon 5 of the ETV6 gene to a site within exon 1B or 2 of the ABL2 gene. This fusion may be associated with acute myeloblastic leukemia.;

Details

Origin ID

C99410;

UMLS CUI

C1833996;

Automatic exact mappings (from CISMeF team)
- Abl protooncogene 2, nonreceptor tyrosine kinase [OMIM gene]
- Ets variant transcription factor 6 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- ETV6/ABL2 Fusion Protein [NCIt concept]
gene_plays_role_in_process
- Tyrosine Phosphorylation [NCIt concept]
related_to_genetic_biomarker
- ABL2 Gene [NCIt concept]
- ETV6 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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