CCND1/FSTL3 Fusion Gene

Preferred Label : CCND1/FSTL3 Fusion Gene;

NCIt synonyms : CCND1-FSTL3 Fusion Gene; CCND1::FSTL3 Fusion Gene;

NCIt definition : A fusion gene that results from a chromosomal translocation t(11;19)(q13;p13) which places the CCND1 gene on the 5' side of the FSTL3 gene. This rearrangement may be associated with B-cell chronic lymphocytic leukemia.;

NCIt note : This translocation disrupts the upstream regulatory region for the FSTL3 gene, which causes aberrant expression of follistatin-related protein 3.;

NCI Metathesaurus CUI : CL433158;

Details

Origin ID

C99370;

UMLS CUI

C1413172;

Automatic exact mappings (from CISMeF team)
- Cyclin d1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
UMLS correspondences (same concept)
- CCND1 gene [LOINC component]
- Cyclin d1 [OMIM gene]
- cyclin D1 [HGNC gene]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
related_to_genetic_biomarker
- CCND1 Gene [NCIt concept]
- FSTL3 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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