MLL/MAML2 Fusion Gene

Preferred Label : MLL/MAML2 Fusion Gene;

NCIt synonyms : MLL-MAML2 Fusion Gene; MAML2/MLL Fusion Gene; KMT2A::MAML2 Fusion Gene; MLL::MAML2 Fusion Gene;

NCIt definition : A fusion gene that results from a chromosomal inversion inv(11)(q21q23) which fuses the exon 7 of the MLL gene to exon 2 of the MAML2 gene. This rearrangement is associated with therapy-related acute leukemia.;

Details

Origin ID

C99357;

UMLS CUI

C2700575;

Automatic exact mappings (from CISMeF team)
- Lysine-specific methyltransferase 2a [OMIM Phenotype]
- Mastermind-like 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- MLL/MAML2 Fusion Protein [NCIt concept]
related_to_genetic_biomarker
- KMT2A Gene [NCIt concept]
- MAML2 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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