MLL/CASC5 Fusion Gene

Preferred Label : MLL/CASC5 Fusion Gene;

NCIt synonyms : MLL/D40 Fusion Gene; MLL-AF15q14 Fusion Gene; MLL-CASC5 Fusion Gene; ALL1-AF15q14 Fusion Gene; MLL/AF15q14 Fusion Gene; AF15Q14/ALL1 Fusion Gene; KMT2A-KNL1 Fusion Gene; KMT2A/KNL1 Fusion Gene; MLL::CASC5 Fusion Gene; KMT2A::KNL1 Fusion Gene;

NCIt definition : A fusion gene that results from a chromosomal translocation t(11;15)(q23;q14) which fuses exon 8 or exon 9 of the MLL gene and exon 10 or exon 12 of the CASC5 gene. This rearrangement may be associated with acute myeloid leukemia and acute lymphoblastic leukemia.;

Details

Origin ID

C99349;

UMLS CUI

C1834587;

Automatic exact mappings (from CISMeF team)
- Kinetochore scaffold 1 [OMIM gene]
- Lysine-specific methyltransferase 2a [OMIM Phenotype]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- MLL/CASC5 Fusion Protein [NCIt concept]
related_to_genetic_biomarker
- KMT2A Gene [NCIt concept]
- KNL1 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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