MLL/ARHGAP26 Fusion Gene

Preferred Label : MLL/ARHGAP26 Fusion Gene;

NCIt synonyms : GRAF/MLL Fusion Gene; MLL-GRAF Fusion Gene; MLL-ARHGAP26 Fusion Gene; MLL/GRAF Fusion Gene; ARHGAP26/MLL Fusion Gene; MLL::ARHGAP26 Fusion Gene; KMT2A::ARHGAP26 Fusion Gene;

NCIt definition : A fusion gene that results from a chromosomal translocation t(5;11)(q31;q23) which fuses the 5' half of the MLL gene to intron 12 of the ARHGAP26 gene. This rearrangement is associated with juvenile myelomonocytic leukemia.;

PubMed : 10908648;

Details

Origin ID

C99337;

UMLS CUI

C1854355;

Automatic exact mappings (from CISMeF team)
- Lysine-specific methyltransferase 2a [OMIM Phenotype]
- Rho gtpase-activating protein 26 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- MLL/ARHGAP26 Fusion Protein [NCIt concept]
related_to_genetic_biomarker
- ARHGAP26 Gene [NCIt concept]
- KMT2A Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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