Preferred Label : Lactobacillus brevis CD2 Lozenge;
NCIt definition : A lozenge containing an extract from the Lactobacillus brevis (L. brevis) with potential
anti-inflammatory activity. As L. brevis CD2 contains high levels of arginine deiminase,
which catalyzes the conversion of arginine to citrulline and ammonia, administration
of this lozenge leads to hydrolysis of arginine in the oral cavity. The growth of
bacteria, which depends on arginine, is halted, polyamine biosynthesis is reduced
and the production of nitric oxide (NO) is reduced. The reduction in NO generation
may further prevent inflammation in the oral cavity. Therefore, this agent may be
able to reduce chemo- and radiotherapy-induced mucositis.;
NCI Metathesaurus CUI : CL433058;
Origin ID : C99229;
UMLS CUI : C3274626;
Semantic type(s)
- concept_is_in_subset
