NCIt definition : Necrosis and softening of the white matter around the ventricles in the brain. It
is usually seen in preterm infants and caused by lack of blood flow and oxygenation
in the periventricular brain parenchyma.;
Alternative definition : NICHD: A form of cerebral white matter injury usually seen in preterm infants that
is characterized by necrotic degeneration or gliosis of white matter adjacent to the
cerebral ventricles, that may evolve into focal cysts.;