Preferred Label : Filgrastim-primed Peripheral Blood Progenitor Cells;
NCIt synonyms : G-CSF-primed Peripheral Blood Progenitor Cells; Filgrastim-primed PBPC; GPBPCI;
NCIt definition : Peripheral blood progenitor cells (PBPC) primed with a recombinant form of the human
granulocyte colony-stimulating factor (filgrastim). As a hematopoietic growth factor,
filgrastim is able to mobilize hematopoietic progenitor cells (HPCs) into the peripheral
blood which allows for an increased number of HPCs upon collection by leukapheresis.
Administration of filgrastim-primed PBPCs following hematopoietic stem cell transplantation
provides increased numbers of progenitor cells which may prevent pancytopenia and
relapse.;
NCI Metathesaurus CUI : CL432855;
Origin ID : C98836;
UMLS CUI : C3274464;
Semantic type(s)
- Cell [UMLS semantic type]
concept_is_in_subset