Acodazole - CISMeF

Preferred Label : Acodazole;

NCIt synonyms : acetamide, N-methyl-N-[4-[(7-methyl-1H-imidazo[4, 5-f]quinolin-9-yl)amino]phenyl]-; 1H-imidazo[4,5-f]quinoline, acetamide deriv;

NCIt definition : A synthetic imidazoquinoline with antineoplastic activity. Acodazole intercalates into DNA, resulting in disruption of DNA replication. Use of this agent has been associated with significant cardiotoxicity. (NCI04);

UNII : 8M28A9O41G;

InChIKey : XJXLRNPVSQADMZ-UHFFFAOYSA-N;

CAS number : 79152-85-5; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 79152-85-5 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Chemical formula : C20H19N5O;

Codes from synonyms : NSC0305884;

Details

Origin ID

C988;

UMLS CUI

C0050565;

Currated CISMeF NLP mapping
- acodazole [MeSH concept]
- acodazole [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- acodazole [MeSH concept]
- acodazole [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_salt_form
- Acodazole Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Acodazole Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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