Acivicin - CISMeF

Preferred Label : Acivicin;

NCIt synonyms : (S-(R*,R*))-4,5-Dihydro-alpha-amino-3-chloro-5-isoxazoleacetic Acid;

NCIt definition : A modified amino acid and structural analog of glutamine. Acivicin inhibits glutamine amidotransferases in the purine and pyrimidine biosynthetic pathways, thereby inhibiting tumor growth in cell lines dependent on glutamine metabolism. (NCI04);

UNII : O0X60K76I6;

InChIKey : QAWIHIJWNYOLBE-OKKQSCSOSA-N;

CAS number : 42228-92-2; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 42228-92-2 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : AT-125; U-42126;

Chemical formula : C5H7ClN2O3;

NSC code : 163501;

Codes from synonyms : NSC0163501;

Details

Origin ID

C986;

UMLS CUI

C0050560;

Currated CISMeF NLP mapping
- acivicin [MeSH concept]
- acivicin [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- acivicin [MeSH concept]
- acivicin [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
is_component_of_chemotherapy_regimen
- Acivicin/Aminosyn [NCIt concept]

Keyword's position in hierarchy(ies) :

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