" /> Aceglatone - CISMeF





Preferred Label : Aceglatone;

NCIt definition : A derivative of D-glucaro-1, 4-lactone with chemopreventive and anti-tumor activities. One of the key processes in which human body eliminates toxic chemicals as well as hormones (such as estrogen) is by glucuronidation. When beta-glucuronidase deconjugates these glucuronides, it prolongs the stay of the hormone or toxic chemical in the body. Elevated beta-glucuronidase activity has been implicated to be associated with an increased risk for hormone-dependent cancers like breast, prostate, and colon cancers. Thereby, aceglatone may suppress the developments of hormone-dependent cancers mediated through beta-glucuronidase inhibition.;

UNII : 347Q3OOJ13;

InChIKey : ZOZKYEHVNDEUCO-DKXJUACHSA-N;

CAS number : 642-83-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 642-83-1 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Glucaron;

Chemical formula : C10H10O8;

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Keyword's position in hierarchy(ies) : arborescence

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12/05/2024


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