Preferred Label : Monoclonal Antibody CEP-37250/KHK2804;
NCIt definition : A humanized monoclonal antibody targeting glycolipids, with potential immunomodulating
and antineoplastic activity. Upon administration, monoclonal antibody CEP-37250/KHK2804
targets and binds to a specific tumor antigen, thereby stimulating the immune system
to exert an antibody-dependent cellular cytotoxicity (ADCC) against the tumor associated
antigen (TAA)-expressing cancer cells. This agent has shown to be active in both wild-type
and mutant K-RAS-expressing colorectal cancer cells.;
Molecule name : CEP-37250/KHK2804;
NCI Metathesaurus CUI : CL432414;
Origin ID : C98296;
UMLS CUI : C3273947;
Semantic type(s)
- chemical_or_drug_has_mechanism_of_action
- concept_is_in_subset
