Preferred Label : Hafnium Oxide-containing Nanoparticles NBTXR3;
NCIt related terms : HAFNIUM OXIDE;
NCIt definition : A suspension of nanoparticles containing inert inorganic hafnium oxide (HfO2) crystals
with potential antineoplastic activity. Upon injection of NBTXR3 in the tumor, the
hafnium oxide-containing nanoparticles accumulate into the tumor cells. Subsequent
application of radiation beams to the tumor tissue causes HfO2 particles to emit huge
amounts of electrons. This results in the formation of free radicals within the tumor
cells, which in turn causes targeted destruction of the cancer cells. Compared to
standard radiotherapy, because of the inert nature of NBTXR3, this agent emits electrons
only during its exposure to radiation which improves radiotherapy efficiency.;
UNII : 3C4Z4KG52T;
CAS number : 12055-23-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 12055-23-1
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G-SRS /a ;
Molecule name : NBTXR3;
NCI Metathesaurus CUI : CL432399;
Origin ID : C98280;
UMLS CUI : C3273933;
Semantic type(s)
- concept_is_in_subset
