SPRY4-IT1 wt Allele

Preferred Label : SPRY4-IT1 wt Allele;

NCIt synonyms : SPRY4IT1; SPRIGHTLY; SPRY4 Intronic Transcript 1 (Non-Protein Coding) Gene; SPRY4 Intronic Transcript 1 wt Allele;

NCIt definition : Human SPRY4-IT1 wild-type allele is located in the vicinity of 5q31.3 and is approximately 700 bp in length. This allele, which encodes SPRY4 intronic transcript 1 (non-protein coding) RNA, may be involved in melanoma cell proliferation and survival.;

NCIt note : Knockdown of SPRY4-IT1 expression results in defects in cell growth, decreased invasion, and increased rates of apoptosis in melanoma cells. (Cancer Research, 2011; 71:3852-3862.);

GenBank Accession Number : AK024556;

PubMed : 21558391;

Details

Origin ID

C98180;

UMLS CUI

C3273863;

Automatic exact mappings (from CISMeF team)
- Spry4 intronic transcript 1, noncoding [OMIM gene]
OMIM relation
- Spry4 intronic transcript 1, noncoding [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_in_chromosomal_location
- 5q31.3 [NCIt concept]
gene_plays_role_in_process
- Tumorigenesis [NCIt concept]

Keyword's position in hierarchy(ies) :

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