NCIt synonyms : Chromosome 15 Open Reading Frame 21 Gene; C15orf21; FLJ39426; High Mobility Group Nucleosomal Binding Domain 2 Pseudogene 46 wt Allele; D-PCa-2;
NCIt definition : Human HMGN2P46 wild-type allele is located in the vicinity of 15q21.1 and is approximately
46 kb in length. This allele, which encodes Dresden prostate carcinoma protein 2,
may play a role in the prostate. Aberrant elevated expression is associated with prostate
carcinoma.;
NCIt note : Both HGNC and EntrezGene categorize the HMGN2P46 gene as a pseudogene; which implies
that no protein product is produced. However, there is a UniProt entry.; Expression of the HMGN2P46 gene was detected at extremely high levels in normal prostate
and prostate carcinoma tissue. Much lower levels ( 2000 fold difference) of gene expression
were observed in other tissues. (Int J Cancer. 2004;109:882-92.);