NCIt definition : Human IGHG1 wild-type allele is located in the vicinity of 14q32.33 and is approximately
7 kb in length. This allele, which encodes immunoglobulin heavy constant gamma 1 protein,
plays a role in immunoglobulin functions. Multiple chromosomal translocations involving
this gene are associated with multiple myeloma; these translocations include t(11;14)(q13;q32)
with the CCND1 gene, t(4;14)(p16.3;q32.3) with the FGFR3 gene, and t(6;14)(p25;q32)
with the IRF4 gene. Another translocation t(1;14)(q25;q32) of this gene and the LHX4
gene is associated with pre-B acute lymphoblastic leukemia.;