Felzartamab - CISMeF

Preferred Label : Felzartamab;

NCIt synonyms : Anti-CD38 Monoclonal Antibody MOR03087;

NCIt related terms : MOR202;

NCIt definition : A fully human monoclonal antibody directed against the cell surface glycoprotein CD-38 with potential antineoplastic activity. Felzartamab specifically binds to CD38 on CD38-positive tumor cells. This may trigger antitumoral antibody-dependent cellular cytotoxicity (ADCC) and may eventually lead to cell lysis in CD38-expressing tumor cells. CD38, a type II transmembrane glycoprotein, is present on various immune cells and hematologic malignancies, and its expression has been correlated with poor prognosis.;

UNII : 3O9FA4XC02;

CAS number : 2197112-39-1;

Molecule name : MOR03087; MOR202; TJ-202;

NCI Metathesaurus CUI : CL430560;

Codes from synonyms : 317;

Details

Origin ID

C97954;

UMLS CUI

C5421254;

Currated CISMeF NLP mapping
- felzartamab [MeSH Supplementary Concept]
- felzartamab [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- felzartamab [MeSH Supplementary Concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients