NCIt definition : A fully human monoclonal antibody directed against the cell surface glycoprotein CD-38
with potential antineoplastic activity. Felzartamab specifically binds to CD38 on
CD38-positive tumor cells. This may trigger antitumoral antibody-dependent cellular
cytotoxicity (ADCC) and may eventually lead to cell lysis in CD38-expressing tumor
cells. CD38, a type II transmembrane glycoprotein, is present on various immune cells
and hematologic malignancies, and its expression has been correlated with poor prognosis.;
UNII : 3O9FA4XC02;
CAS number : 2197112-39-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 2197112-39-1
alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo
G-SRS /a ;