ZNF384 wt Allele

Preferred Label : ZNF384 wt Allele;

NCIt synonyms : CAGH1; NMP4; TNRC1; CAGH1A; CIZ; FLJ59043; ERDA2; Trinucleotide Repeat Containing 1 Gene; Zinc Finger Protein 384 wt Allele;

NCIt definition : Human ZNF384 wild-type allele is located in the vicinity of 12p12 and is approximately 23 kb in length. This allele, which encodes zinc finger protein 384, plays a role in both the modulation of transcription and DNA binding. At least 3 translocations affecting this gene are associated with acute lymphoblastic leukemia. Translocation t(12;17)(p13;q11) fuses the gene to the TAF15 gene, t(12;19)(p13;p13) generates a fusion with the TCF3 gene and t(12;22)(p13;q12) fuses this gene and the EWSR1 gene.;

GenBank Accession Number : U80738;

Details

Origin ID

C97883;

UMLS CUI

C3273675;

OMIM relation
- Zinc finger protein 384 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 12p12 [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- B Acute Lymphoblastic Leukemia with ZNF384 Rearrangement [NCIt concept]
gene_plays_role_in_process
- DNA Binding [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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