POU2AF1 wt Allele

Preferred Label : POU2AF1 wt Allele;

NCIt synonyms : OBF-1; POU Domain Class 2, Associating Factor 1 Gene; POU Class 2 Associating Factor 1 wt Allele; OBF1; OCAB; BOB1;

NCIt definition : Human POU2AF1 wild-type allele is located in the vicinity of 11q23.1 and is approximately 103 kb in length. This allele, which encodes POU domain class 2-associating factor 1 protein, plays a role in both transcriptional modulation and the B-cell response to antigen exposure. A chromosomal translocation t(3;11)(q27;q23.1) of this gene and the BCL6 gene may be associated with both non-Hodgkin lymphoma and B-cell leukemia.;

GenBank Accession Number : NM_006235;

Details

Origin ID

C97731;

UMLS CUI

C3273596;

OMIM relation
- Pou domain, class 2, associating factor 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 11q23.1 [NCIt concept]
gene_plays_role_in_process
- Humoral Immunity [NCIt concept]
- Transcriptional Activation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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