NCIt related terms : 3-METHOXY-4-NITRO-ESTRA-1,3,5(10)-TRIEN-17-ONE;
NCIt definition : A synthetic derivative of estradiol. 4-nitroestrone 3-methyl ether inhibits estrogen
sulfotransferase (EST), a progesterone-induced secretory endometrial enzyme which
affects estrogen receptor levels. This agent has been shown to be an effective growth
inhibitor of some chemically induced animal mammary tumors. (NCI04);