Preferred Label : Brain Tumor Initiating Cell Vaccine;
NCIt synonyms : BTIC Vaccine;
NCIt definition : A cell-based cancer vaccine comprised of brain tumor initiating cells (BTICs), with
potential immunostimulating and antineoplastic activity. BITCs are from the glioblastoma
multiforme (GBM) cell line GBM-6 and contain glioma stem-like cell-associated antigens.
Upon administration, the BITC vaccine may stimulate a specific anti-tumoral cytotoxic
T-lymphocyte (CTL) response against brain tumor cancer cells and brain tumor stem
like cells, resulting in tumor cell lysis. BITC have unique antigenicity and have
the ability to self-renew; vaccination against BITC antigens may kill these cells
and may prevent tumor recurrences.;
NCI Metathesaurus CUI : CL430321;
Origin ID : C97666;
UMLS CUI : C3273556;
Semantic type(s)
- concept_is_in_subset
