Preferred Label : Cyclin B1 Peptide-pulsed Autologous Dendritic Cell Vaccine;
NCIt synonyms : CCNB1 Peptide-pulsed Autologous Dendritic Cell Vaccine;
NCIt definition : A cell-based cancer vaccine comprised of autologous dendritic cells (DCs) pulsed with
cyclin B1 peptide, with potential immunostimulatory and antineoplastic activities.
Upon administration, cyclin B1 peptide-pulsed autologous dendritic cell vaccine may
stimulate anti-tumoral cytotoxic T lymphocyte (CTL) and anti-cyclin B1 antibody responses
against cyclin B1-expressing cancer cells, resulting in tumor cell lysis. Cyclin B1,
a key regulator of the cell cycle and cell division, is overexpressed in a variety
of cancer cells.;
NCI Metathesaurus CUI : CL430320;
Origin ID : C97665;
UMLS CUI : C3273555;
Semantic type(s)
- concept_is_in_subset
