NCIt definition : An orally available, highly water-soluble lysine prodrug of the synthetic small molecule
BAL27862 with potential antitumor activity. Upon administration of lisavanbulin and
conversion into the active form BAL27862, this agent binds to tubulin at a site distinct
from the vinca-alkaloid-binding site, and prevents tubulin polymerization and destabilizes
microtubules, ultimately leading to cell cycle arrest, blockage of cell division and
an induction of cell death in cancer cells.;