" /> Lisavanbulin - CISMeF





Preferred Label : Lisavanbulin;

NCIt synonyms : (2S)-2,6-Diamino-N-(4-(2-(2-(4-((2-cyanoethyl)amino)-1,2,5-oxadiazol-3-yl)-1H-benzimidazol-1-yl)acetyl)phenyl)hexanamide;

NCIt definition : An orally available, highly water-soluble lysine prodrug of the synthetic small molecule BAL27862 with potential antitumor activity. Upon administration of lisavanbulin and conversion into the active form BAL27862, this agent binds to tubulin at a site distinct from the vinca-alkaloid-binding site, and prevents tubulin polymerization and destabilizes microtubules, ultimately leading to cell cycle arrest, blockage of cell division and an induction of cell death in cancer cells.;

UNII : 5PT0QP06X5;

InChIKey : NIPZLALJRAHABJ-IBGZPJMESA-N;

CAS number : 1263384-43-5; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1263384-43-5 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : BAL-101553;

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12/05/2024


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