" /> LPP wt Allele - CISMeF





Preferred Label : LPP wt Allele;

NCIt synonyms : LIM Domain Containing Preferred Translocation Partner in Lipoma wt Allele; FLJ30652; DKFZp779O0231; FLJ41512;

NCIt definition : Human LPP wild-type allele is located in the vicinity of 3q28 and is approximately 737 kb in length. This allele, which encodes lipoma-preferred partner protein, may play a role in cell motility and cell shape. A chromosomal translocation t(3;12)(q27-q28;q13-q15) of this gene with the HMGA2 gene is associated with lipoma and translocation t(3;11)(q28;q23) of this gene with the MLL gene is associated with acute monoblastic leukemia.;

NCIt note : The LPP and HMGA2 genes are involved in other chromosomal aberrations; t(3;12)(q27-q28;q14-q15) is associated with pulmonary chondroid hamartoma and t(3;12)(q28;q14) is associated with a rare disease, parosteal lipoma.;

GenBank Accession Number : AL833171;

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29/05/2025


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