HLF wt Allele - CISMeF

Preferred Label : HLF wt Allele;

NCIt synonyms : HLF, PAR BZIP Transcription Factor Gene; MGC33822; HLF Transcription Factor, PAR BZIP Family Member wt Allele; Hepatic Leukemia Factor Gene; PAR BZIP Transcription Factor Gene;

NCIt definition : Human HLF wild-type allele is located in the vicinity of 17q22 and is approximately 60 kb in length. This allele, which encodes hepatic leukemia factor, plays a role in the modulation of transcription. A chromosomal translocation t(17;19)(q22;p13.3) with the TCF3 gene is associated with childhood pre-B-cell acute lymphoblastic leukemia.;

GenBank Accession Number : NM_002126;

Details

Origin ID

C97557;

UMLS CUI

C3273488;

Automatic exact mappings (from CISMeF team)
- HLF transcription factor, PAR bZIP family member [ORDO Gene]
OMIM relation
- Hepatic leukemia factor [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- B Acute Lymphoblastic Leukemia with HLF Rearrangement [NCIt concept]
gene_plays_role_in_process
- DNA Binding [NCIt concept]
- Development [NCIt concept]
- Developmental Process [NCIt concept]
- Protein Dimerization [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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