FNBP1 wt Allele

Preferred Label : FNBP1 wt Allele;

NCIt synonyms : Formin Binding Protein 1 wt Allele; MGC126804; KIAA0554; FBP17;

NCIt definition : Human FNBP1 wild-type allele is located in the vicinity of 9q34 and is approximately 156 kb in length. This allele, which encodes formin-binding protein 1, is involved in both actin remodeling and endocytosis. A chromosomal translocation t(9;11)(q34;q23) of this gene and the MLL gene is associated with rare cases of acute myelogenous leukemia.;

NCIt note : A complex chromosomal aberration ins(11;9)(q23;q34)inv(11)(q13q23) fuses the FNBP1 gene and the MLL gene and is associated with rare cases of acute myelogenous leukemia. (Proc Natl Acad Sci U S A. 2001; 98:8756-8761.);

GenBank Accession Number : AB011126;

Details

Origin ID

C97541;

UMLS CUI

C3273478;

OMIM relation
- Formin-binding protein 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 9q34 [NCIt concept]
gene_plays_role_in_process
- Endocytotic Process [NCIt concept]
- Protein-Protein Interaction [NCIt concept]

Keyword's position in hierarchy(ies) :

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