GMPS wt Allele

Preferred Label : GMPS wt Allele;

NCIt synonyms : GMP Synthase Gene; Guanine Monphosphate Synthetase wt Allele; Guanosine 5'-Monophosphate Synthase Gene;

NCIt definition : Human GMPS wild-type allele is located in the vicinity of 3q24 and is approximately 70 kb in length. This allele, which encodes GMP synthase [glutamine-hydrolyzing], is involved in the modulation of purine synthesis. A chromosomal translocation t(3,11)(q25,q23) of this gene and the MLL gene is associated with treatment-related acute myeloid leukemia.;

GenBank Accession Number : U10860;

Details

Origin ID

C97523;

UMLS CUI

C3273469;

OMIM relation
- Guanine monophosphate synthetase [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 3q24 [NCIt concept]
gene_is_element_in_pathway
- Drug Metabolism by Non-CYP450 Enzymes Pathway [NCIt concept]
- Purine Metabolism Pathway [NCIt concept]
gene_plays_role_in_process
- Nucleotide Biosynthesis Process [NCIt concept]

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