NCIt definition : Human ATIC wild-type allele is located in the vicinity of 2q35 and is approximately
38 kb in length. This allele, which encodes bifunctional purine biosynthesis protein
PURH, is involved in the synthesis of purines. A chromosomal inversion inv(2)(p23q35)
involving this gene and the ALK gene is associated with rare cases of ALK-positive
anaplastic large cell lymphoma.;