" /> BCL11A wt Allele - CISMeF





Preferred Label : BCL11A wt Allele;

NCIt synonyms : FLJ34997; ZNF856; BCL11A-XL; FLJ10173; CTIP1; BCL11A-S; BCL11A-L; HBFQTL5; Ecotropic Viral Integration Site 9 Gene; EVI9; KIAA1809; B-Cell CLL/Lymphoma 11A (Zinc Finger Protein) Gene; SMARCM1; BAF Chromatin Remodeling Complex Subunit BCL11A wt Allele; B Cell CLL/Lymphoma 11A Gene; BCL11A, BAF Complex Component Gene; DILOS; BCL11a-M; EVI9, Mouse, Homolog of Gene; CTIP1, Mouse, Homolog of Gene;

NCIt definition : Human BCL11A wild-type allele is located in the vicinity of 2p16.1 and is approximately 102 kb in length. This allele, which encodes B-cell lymphoma/leukemia 11A protein, plays a role in both lymphopoiesis and cell shape. Overexpression of the gene is associated with a translocation t(2;14)(p13;q32.3) as well as chronic lymphocytic leukemia and other B-cell malignancies.;

NCIt note : Multiple transcript variants encoding several different isoforms have been found for the BCL11A gene. (EntrezGene); Variation of the BCL11A gene underlies the fetal hemoglobin quantitative trait locus 5 which is associated with variation in the production of erythrocytes containing measurable amounts of fetal hemoglobin (HbF). (UniProt);

GenBank Accession Number : AJ404611;

Details


Keyword's position in hierarchy(ies) : arborescence

You can consult :


Nous contacter.
30/04/2024


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.