MLLT11 wt Allele

Preferred Label : MLLT11 wt Allele;

NCIt synonyms : ALL1 Fused Gene from Chromosome 1q Gene; RP11-316M1.10; AF1Q; Myeloid/Lymphoid or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila); Translocated to, 11 wt Allele;

NCIt definition : Human MLLT11 wild-type allele is located in the vicinity of 1q21 and is approximately 11 kb in length. This allele, which encodes protein AF1q, plays a role in both depolarization of and release of cytochrome c by the mitochondrion. The gene is involved in a translocation t(1;11)(q21;q23) with the MLL gene that is associated with acute leukemia.;

GenBank Accession Number : BC006471;

Details

Origin ID

C97388;

UMLS CUI

C3273389;

Automatic exact mappings (from CISMeF team)
- Mllt11 transcription factor 7 cofactor [OMIM gene]
OMIM relation
- Mllt11 transcription factor 7 cofactor [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 1q21 [NCIt concept]
gene_plays_role_in_process
- Positive Regulation of Apoptosis [NCIt concept]
- Transcriptional Activation [NCIt concept]

Keyword's position in hierarchy(ies) :

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