" /> Cobicistat - CISMeF





Preferred Label : Cobicistat;

NCIt synonyms : 2,7,10,12-Tetraazatridecanoic Acid, 12-Methyl-13-(2-(1-methylethyl)-4-thiazolyl)-9-(2-(4-morpholinyl)ethyl)-8,11-dioxo-3,6-bis(phenylmethyl)-, 5-Thiazolylmethyl Ester, (3R,6R,9S)-;

NCIt definition : A cytochrome P450 3A (CYP3A) inhibitor that can be used to enhance the pharmacokinetic profile of certain anti-HIV-1 agents. Upon administration, cobicistat inhibits the liver enzyme CYP3A4 and limits the breakdown of co-administered agents that are metabolized by CYP3A4, and increases the concentration, systemic exposure and efficacy of the co-administered agent.;

UNII : LW2E03M5PG;

InChIKey : ZCIGNRJZKPOIKD-CQXVEOKZSA-N;

CAS number : 1004316-88-4;

Drug name : Tybost;

Molecule name : GS 9350;

Chemical formula : C40H53N7O5S2;

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04/05/2025


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