Allogeneic AML Antigen-expressing Dendritic Cell Vaccine

Preferred Label : Allogeneic AML Antigen-expressing Dendritic Cell Vaccine;

NCIt synonyms : Allogeneic Acute Myeloid Leukemia Antigen-expressing Dendritic Cell Vaccine;

NCIt definition : A cancer vaccine consisting of allogeneic, immortalized dendritic precursor cells derived from a patient with acute myelogenous leukemia (AML), with potential immunostimulatory and antineoplastic activities. Upon ex vivo stimulation and expansion of the precursor cells into mature, fully functional dendritic cells (DCs) and subsequent administration, the allogeneic AML antigen-expressing DC vaccine may elicit a potent cytotoxic T-cell (CTL) and antibody response against AML antigen-expressing cells, resulting in tumor cell death.;

Drug name : DCOne;

Molecule name : DCP-001;

NCI Metathesaurus CUI : CL429791;

Details

Origin ID

C97265;

UMLS CUI

C3273316;

Semantic type(s)
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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