ZFYVE19 wt Allele

Preferred Label : ZFYVE19 wt Allele;

NCIt synonyms : MPFYVE; FLJ14840; PFIC9; Zinc Finger FYVE-Type Containing 19 wt Allele; ANCHR; Zinc Finger, FYVE Domain Containing 19 Gene;

NCIt definition : Human ZFYVE19 wild-type allele is located in the vicinity of 15q15.1 and is approximately 8 kb in length. This allele, which encodes abscission/nocut checkpoint regulator protein, may play a role in the response to DNA damage and in the regulation of cytokinesis. Mutation of the gene is associated with progressive familial intrahepatic cholestasis 9 and a cytogenetic abnormality involving this gene and the KMT2A gene, translocation t(11;15)(q23;q14), is associated with acute myeloblastic leukemia.;

GenBank Accession Number : AK027746;

Details

Origin ID

C97224;

UMLS CUI

C3273287;

OMIM relation
- Zinc finger fyve domain-containing protein 19 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_plays_role_in_process
- Cell Cycle Checkpoint [NCIt concept]
- Cell Cycle Process [NCIt concept]
- Cell Cycle Regulation Process [NCIt concept]
- Cytokinesis [NCIt concept]

Keyword's position in hierarchy(ies) :

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