KLK10 wt Allele

Preferred Label : KLK10 wt Allele;

NCIt synonyms : NES1; Breast Normal Epithelial Cell Associated Serine Protease Gene; Kallikrein 10 wt Allele; PRSSL1;

NCIt definition : Human KLK10 wild-type allele is located in the vicinity of 19q13 and is approximately 7 kb in length. This allele, which encodes kallikrein-10 protein, is involved in both tumor suppression and proteolysis.;

NCIt note : Expression of the KLK10 gene is down-regulated during breast cancer progression. (UniProt); The methylation status of the KLK10 gene in breast cancer may be associated with a higher metastatic potential. (Sci. Transl. Med. 2011; 3. DOI: 10.1126/scitranslmed.3001875.);

GenBank Accession Number : AF024605;

Details

Origin ID

C97207;

UMLS CUI

C3273278;

OMIM relation
- Kallikrein-related peptidase 10 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 19q13 [NCIt concept]
gene_plays_role_in_process
- Hydrolysis [NCIt concept]
- Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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