SOX8 wt Allele

Preferred Label : SOX8 wt Allele;

NCIt synonyms : MGC24837; SRY (Sex Determining Region Y)-Box 8 wt Allele;

NCIt definition : Human SOX8 wild-type allele is located in the vicinity of 16p13.3 and is approximately 5 kb in length. This allele, which encodes transcription factor SOX-8 protein, plays a role in both embryonic development and the positive regulation of transcription.;

NCIt note : The methylation status of the SOX8 gene in breast cancer may be associated with a higher metastatic potential. (Sci. Transl. Med. 2011; 3. DOI: 10.1126/scitranslmed.3001875.);

GenBank Accession Number : AF164104;

Details

Origin ID

C97204;

UMLS CUI

C3273277;

OMIM relation
- Sry-box 8 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 16p13.3 [NCIt concept]
gene_plays_role_in_process
- DNA Binding [NCIt concept]
- Signal Transduction [NCIt concept]
- Transcriptional Activation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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