Preferred Label : 5-Fluorouracil/Salicylic Acid Topical Solution;
NCIt synonyms : Low-dose 5-Fluorouracil/Salicylic Acid;
NCIt definition : A topical formulation containing 0.5 % of antimetabolite 5-fluorouracil (5-FU) and
10% of salicylic acid, with potential antimitotic and keratolytic activity. Upon cutaneous
application, 5-FU in the 5-fluorouracil/salicylic acid topical solution impedes pyrimidine
metabolism thereby inhibiting cell growth, while the salicylic acid induces anti-inflammatory
response and results in keratolytic effect. This may result in the breakdown of keratinocytes
and prevent proliferation of keratinocytes locally.;
Drug name : Actikerall;
Molecule name : LAS 41005;
NCI Metathesaurus CUI : CL429685;
Origin ID : C97131;
UMLS CUI : C3273247;
Semantic type(s)
- concept_is_in_subset
