Preferred Label : Nibrozetone;
NCIt synonyms : Radiosensitizer RRx-001;
NCIt definition : A dinitroazetidine derivative with potential radiosensitizing activity. Upon administration,
nibrozetone is able to dilate blood vessels, thereby increasing tumor blood flow and
thus improving oxygenation to the tumor site. By increasing oxygen levels, these tumor
cells may be more susceptible to radiation therapy. Tumor hypoxia is correlated with
tumor aggressiveness, metastasis and resistance to radiotherapy.;
UNII : 7RPW6SU9SC;
CAS number : 925206-65-1;
Molecule name : RRx-001;
Origin ID : C97130;
UMLS CUI : C5910037;
Semantic type(s)
- UMLS correspondences (same concept)
- RRx-001 [MeSH Supplementary Concept]
- concept_is_in_subset
