Technetium Tc 99m Galactosyl Human Serum Albumin

Preferred Label : Technetium Tc 99m Galactosyl Human Serum Albumin;

NCIt synonyms : 99mTc-GSA; Tc-99m GSA;

NCIt definition : A colloid formulation of human galactosyl serum albumin (GSA) conjugated to the chelating agent diethylene-triaminepentaacetic acid (DTPA) and complexed to the gamma-emitting isotope technetium-99m (99mTc-GSA) with potential diagnostic imaging activity. Upon intravenous administration, the galactosyl moiety of 99mTc-GSA binds to asialoglycoprotein receptors (ASGPR) located on hepatic cells. Upon SPECT (Single Photon Emission Computed Tomography) imaging, liver function can be assessed. The expression of asialoglycoprotein receptors (ASGPR), which are solely found on the plasma membrane of mammalian hepatocytes, is associated with hepatic function.;

NCI Metathesaurus CUI : CL429643;

Details

Origin ID

C97036;

UMLS CUI

C0145052;

Currated CISMeF NLP mapping
- technetium tc 99m DTPA-galactosyl-human serum albumin [MeSH Supplementary Concept]
- technetium tc 99m DTPA-galactosyl-human serum albumin [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Indicator, Reagent, or Diagnostic Aid [UMLS semantic type]
UMLS correspondences (same concept)
- technetium tc 99m DTPA-galactosyl-human serum albumin [MeSH Supplementary Concept]
- technetium tc 99m DTPA-galactosyl-human serum albumin [MeSH concept]
concept_is_in_subset
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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