Extrahepatic Bile Duct Neuroendocrine Carcinoma

Preferred Label : Extrahepatic Bile Duct Neuroendocrine Carcinoma;

NCIt synonyms : Extrahepatic Bile Duct Poorly Differentiated Endocrine Carcinoma; Extrahepatic Bile Duct NEC; Extrahepatic Bile Duct High Grade Neuroendocrine Carcinoma; Extrahepatic Bile Duct G3;

NCIt definition : An aggressive, high-grade, and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the extrahepatic bile ducts. The mitotic count is more than 20 per 10 HPF. It is classified as either small or large cell neuroendocrine carcinoma based on the size of the malignant cells, the prominence of the nucleoli, and the amount of cytoplasm.;

Neoplastic status : Malignant;

Details

Origin ID

C96956;

UMLS CUI

C3273140;

Disease excludes abnormal cell
- Large Osteoclastic Giant Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Excludes anatomical site(s)
- Head and Neck [NCIt concept]
- Lung [NCIt concept]
Has associated anatomic sites
- Bile Duct [NCIt concept]
- Biliary Tract [NCIt concept]
- Digestive System [NCIt concept]
- Extrahepatic Bile Duct [NCIt concept]
- Hepatobiliary System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Intermediate Grade Neuroendocrine Lesion [NCIt concept]
- Low Grade Neuroendocrine Lesion [NCIt concept]
- Low Mitotic Activity [NCIt concept]
- Well Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Endocrine Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Malignant Neuroendocrine Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Endocrine Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Neuroendocrine Cell [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Endocrine Differentiation [NCIt concept]
- Epithelial Component Present [NCIt concept]
- High Mitotic Activity [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Neuroendocrine Differentiation [NCIt concept]
- Poorly Differentiated Neuroendocrine Lesion [NCIt concept]
- Severe Cytologic Atypia [NCIt concept]
disease_has_grade
- Grade 3 [NCIt concept]
- High Grade [NCIt concept]
disease_has_normal_cell_origin
- Endocrine Cell of the Digestive System [NCIt concept]
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Bile Duct Epithelium [NCIt concept]
- Epithelial Tissue [NCIt concept]
- Extrahepatic Bile Duct Epithelium [NCIt concept]
disease_has_primary_anatomic_site
- Bile Duct [NCIt concept]
- Biliary Tract [NCIt concept]
- Digestive System [NCIt concept]
- Extrahepatic Bile Duct [NCIt concept]
- Pancreatobiliary System [NCIt concept]

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