" /> Temanogrel Hydrochloride - CISMeF





Preferred Label : Temanogrel Hydrochloride;

NCIt synonyms : Temanogrel; 3-methoxy-n-(3-(1-methyl-1h-pyrazol-5-yl)-4-(2-(morpholin-4-yl)ethoxy)phenyl)benzamide; Benzamide, 3-methoxy-n-(3-(1-methyl-1h-pyrazol-5-yl)-4-(2-(4-morpholinyl)ethoxy)phenyl)-;

NCIt definition : The hydrochloride salt form of temanogrel, an orally bioavailable, selective inverse agonist of 5-hydroxytryptamine receptor 2A (5-HT2A), with potential anti-thrombotic and vasodilating activities. Upon oral administration, temanogrel targets, binds to and inhibits 5-HT2A expressed on platelet surfaces and in smooth muscle cells, thereby inhibiting 5-HT-mediated platelet aggregation and vasoconstriction. This may attenuate platelet aggregation and vasoconstriction, and improve blood flow.;

UNII : 5QEY8NZP3T;

InChIKey : APWHJJLFCMBWQT-UHFFFAOYSA-N;

CAS number : 957466-27-2;

Molecule name : APD-791;

Chemical formula : C24H28N4O4.ClH;

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10/05/2025


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